Antiperinuclear factor in juvenile rheumatoid arthritis.
نویسندگان
چکیده
منابع مشابه
Antiperinuclear factor in juvenile rheumatoid arthritis.
The serological diagnosis of juvenile rheumatoid arthritis (JRA) is difficult, with only 7-10% of patients 19S IgM rheumatoid factor positive. About 60-70% of patients are positive for hidden 19S IgM rheumatoid factor, but this test requires serum separation and is not available in most laboratories. Antiperinuclear factor has been described in both seropositive and seronegative adult patients ...
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Sir: Nesher et al recently described the first comprehensive series considering antiperinuclear factor in juvenile chronic arthritis (JCA). They found an overall positivity of 34%; in patients with the polyarticular type of the disease 16/28 patients were positive.' Our results are at variance with these data: in a group of 313 patients only three were positive, all of them children with polyar...
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Tests for antiperinuclear factor (APF) demonstrable by indirect immunofluorescence (IF) on smears of human buccal mucosal cells and for antibodies to keratin (AKA) detected on cryostat sections of rat oesophagus were performed on serum from 102 cases of rheumatoid arthritis (RA) and 117 controls. APF was detected in 92% of the cases of RA; positive tests obtained with non-RA sera were generally...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1992
ISSN: 0003-4967
DOI: 10.1136/ard.51.3.350